CCBP samples as of 03/31/2026. The diagnosis reflects the most recent diagnosis in our database. We do track diagnoses longitudinally, so we can identify patients who entered the study with a different initial diagnosis. There’s one 1 patient with dystonia syndrome, 1 with FND, 1 with PPA (primary progressive aphasia) and 1 with apraxia of speech.

We store blood in PAXgene tubes for later RNA extraction. Stool samples are collected and stored in OMNIgene-GUT OMR-200 tubes (https://www.dnagenotek.com/us/products/collection-microbiome/omnigene-gut/OMR-200). DNA stored at -20 °C; PBMC extracted immediately upon blood collection and stored in liquid nitrogen at -175 °C; plasma, blood in PAXgene tubes, urine, stool samples and CSF at -80 °C.

ET = essential tremor; LKO = leukodystrophy; PPA = primary progressive aphasia; PBMC = peripheral blood mononuclear cells.