
Cincinnati Cohort Biomarker Program
Vision
To realize the potential of precision medicine for patients living with neurodegenerative diseases
To characterize patients affected by neurodegenerative diseases –not to understand diseases, but to understand how individuals are affected by them.
Mission
To re-define Parkinson disease and Alzheimer’s disease from a biological standpoint classifying individual patients into distinctive molecular subtypes
To identify small but molecularly suitable subsets of subjects for embedded proof-of-concept adaptive clinical trials
To use biological data to match the right patient to the right therapy
STUDY TIMELINE
Months 0-6: Administrative preparation; database creation
Months 6-72: Recruitment of 4000 patients and 1000 healthy controls with initial annual follow-up
Months 72-120: Finish Data Collection, completion of data analysis and follow-up